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Seann Mulcahy

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Photo of faculty memberAssociate Professor

Contact Information:

smulcahy@providence.edu
401-865-1280
Albertus Magnus Hall 319

Education:

Postdoctoral Research - Yale University (2010) and Boston University (2012)
Ph.D. - University of Pennsylvania (2009)
B.S. - University of Richmond (2004)

Area(s) of Expertise:

Organic chemistry, medicinal chemistry, chemical biology, chemical education

Awards and Honors:

Jean Dreyfus Lectureship for Undergraduate Institutions Award - Camille and Henry Dreyfus Foundation
Facilitating Research at Undergraduate Institutions Award - National Science Foundation Division of Chemistry
Proposal Development Award - NIH RI-INBRE
Undergraduate New Investigator Award - American Chemical Society Petroleum Research Fund
Faculty Early Career Development Award - NIH RI-INBRE

Selected Publications:

Mulcahy, Seann., Varelas, Jonathan., Khanal, Satyam., O'Donnell, Michael. (2015). Concise Synthesis of Annulated Pyrido[3,4-b]indoles via Rh(I)-Catalyzed Cyclization. Organic Letters17 (21), 5512-5514.

Roggero, Chad., Giulietti, Jennifer., Mulcahy, Seann. (2014). Efficient synthesis of eudistomin U and evaluation of its cytotoxicity. Bioorganic and Medicinal Chemistry Letters24 (15), 3549-3551.

Mulcahy, Seann., Varelas, Jonathan. (2013). Three-step synthesis of an annulated β-carboline via palladium catalysis. Tetrahedron Letters54 (48), 6599-6601.

Mulcahy, Seann., Woo, Christina., Ding, Weidong., Ellestad, George., Herzon, Seth. (2012). Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the Kinamycins and Lomaiviticins. Chemical Science3, 1070-1074.

Gong, Lei., Mulcahy, Seann., Devarajan, Deepa., Harms, Klaus., Frenking, Gernot., Meggers, Eric. (2010). Chiral Salicyloxazolines as Auxiliaries for the Asymmetric Synthesis of Ruthenium Polypyridyl Complexes. Inorganic Chemistry49, 7692-7699.

Mulcahy, Seann., Gruendler, Katharina., Frias, Corazon., Prokop, Aram., Meggers, Eric. (2010). Discovery of a Strongly Apoptotic Ruthenium Complex Through Combinatorial Coordination Chemistry. Dalton Transactions39, 8177-8182.

Recent Presentations:

Mulcahy, Seann., Roggero, Chad., Giulietti, Jennifer., Giulietti, Jennifer., 248th National Meeting of the American Chemical Society, American Chemical Society, San Francisco, CA, "Suzuki Cross Coupling Strategy for the Synthesis of 1-Aryl and 1-Heteroaryl Eudistomin U Analogs". August, 2014.

Varelas, Jonathan., O'Donnell, Michael., Khanal, Satyam., Khanal, Satyam., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Convenient synthesis of annulated β-carbolines via transition metal-catalyzed [2+2+2] cyclization". March, 2014.

Schwarzer, Cody., Szeto, Howard., Gale-Day, Zachary., Gale-Day, Zachary., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Diastereoselective synthesis of unnatural alkaloids". March, 2014.

Roggero, Chad., Giulietti, Jennifer., Mulcahy, Seann., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Synthesis of β-carboline natural products via divergent palladium catalysis". March, 2014.

Giulietti, Jennifer., Roggero, Chad., Mulcahy, Seann., 247th National Meeting of the American Chemical Society, American Chemical Society, Dallas, TX, "Synthesis, cytotoxicity, and DNA-binding studies of the natural product eudistomin U". March, 2014.